02/04/2008
Nefrotossicità da tenofovir
Tenofovir nephrotoxicity: focusing research questions and putting them into clinical context.Szczech LA.J Infect Dis. 2008 Jan 1;197(1):7-9
13/03/2008
Review sistematica su fibrotest e fibroscan
FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy. Shaheen AA, Wan AF, Myers RP. Am J Gastroenterol. 2007 Nov;102(11):2589-600.
13/03/2008
Review sistematica su fibrotest e fibroscan
FibroTest and FibroScan for the prediction of hepatitis C-related fibrosis: a systematic review of diagnostic test accuracy. Shaheen AA, Wan AF, Myers RP. Am J Gastroenterol. 2007 Nov;102(11):2589-600.
11/03/2008
Iron-overload epatico e mutazione C282Y
Iron-overload-related disease in HFE hereditary hemochromatosis.Allen KJ, Gurrin LC, Constantine CC, Osborne NJ, Delatycki MB, Nicoll AJ, McLaren CE, Bahlo M, Nisselle AE, Vulpe CD, Anderson GJ, Southey MC, Giles GG, English DR, Hopper JL, Olynyk JK, Powell LW, Gertig DM. N Engl J Med. 2008 Jan 17;358(3):221-30.
11/03/2008
Iron-overload epatico e mutazione C282Y
Iron-overload-related disease in HFE hereditary hemochromatosis.Allen KJ, Gurrin LC, Constantine CC, Osborne NJ, Delatycki MB, Nicoll AJ, McLaren CE, Bahlo M, Nisselle AE, Vulpe CD, Anderson GJ, Southey MC, Giles GG, English DR, Hopper JL, Olynyk JK, Powell LW, Gertig DM. N Engl J Med. 2008 Jan 17;358(3):221-30.
09/03/2008
RMN sempre più accurata nello staging delle epatopatie croniche.
Magnetic resonance imaging of hepatic fibrosis: emerging clinical applications.Talwalkar JA, Yin M, Fidler JL, Sanderson SO, Kamath PS, Ehman RL. Hepatology. 2008 Jan;47(1):332-42.
09/03/2008
RMN sempre più accurata nello staging delle epatopatie croniche.
Magnetic resonance imaging of hepatic fibrosis: emerging clinical applications.Talwalkar JA, Yin M, Fidler JL, Sanderson SO, Kamath PS, Ehman RL. Hepatology. 2008 Jan;47(1):332-42.
07/03/2008
Utile lo screening in soggetti a rischio per infezione da HCV
Outcome of screening for hepatitis C virus infection based on risk factors.Mallette C, Flynn MA, Promrat K. Am J Gastroenterol. 2008 Jan;103(1):131-7
07/03/2008
Utile lo screening in soggetti a rischio per infezione da HCV
Outcome of screening for hepatitis C virus infection based on risk factors.Mallette C, Flynn MA, Promrat K. Am J Gastroenterol. 2008 Jan;103(1):131-7
05/03/2008
FDA alert: Natalizumab causa significativi danni epatici
Reports Of Clinically Significant Liver InjuryROCKVILLE, Md., Feb. 27, 2008-Biogen Idec, Elan and FDA notified healthcare professionals of reports of clinically significant liver injury, including markedly elevated serum hepatic enzymes and elevated total bilirubin, occurred as early as six days after the first dose of Tysabri. The combination of transaminase elevations and elevated bilirubin without evidence of obstruction is recognized as an important predictor of severe liver injury that may lead to death or the need for a liver transplant in some patients. T
20/02/2008
Epatite acuta da HCV: fattori che condizionano la clearance virale
Acute hepatitis C in a contemporary US cohort: modes of acquisition and factors influencing viral clearance. Wang CC, Krantz E, Klarquist J, Krows M, McBride L, Scott EP, Shaw-Stiffel T, Weston SJ, Thiede H, Wald A, Rosen HR. J Infect Dis. 2007 Nov 15;196(10):1474-82.
13/02/2008
Il baclofene aiuta i cirrotici a mantenere l’astinenza dall’alcol
Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study.Addolorato G, Leggio L, Ferrulli A, Cardone S, Vonghia L, Mirijello A, Abenavoli L, D'Angelo C, Caputo F, Zambon A, Haber PS, Gasbarrini G. Lancet. 2007 Dec 8;370(9603):1915-22.
10/02/2008
La SVR migliora l’outcome della cirrosi da HCV?
Sustained virologic response and clinical outcomes in patients with chronic hepatitis C and advanced fibrosis. Veldt BJ, Heathcote EJ, Wedemeyer H, Reichen J, Hofmann WP, Zeuzem S, Manns MP, Hansen BE, Schalm SW, Janssen HL. Ann Intern Med. 2007 Nov 20;147(10):677-84.
05/02/2008
Nuovo trattamento della piastrinopenia nei cirrotici....
Eltrombopag for thrombocytopenia in patients with cirrhosis associated with hepatitis C.McHutchison JG, Dusheiko G, Shiffman ML, Rodriguez-Torres M, Sigal S, Bourliere M, Berg T, Gordon SC, Campbell FM, Theodore D, Blackman N, Jenkins J, Afdhal NH; TPL102357 Study Group. N Engl J Med. 2007 Nov 29;357(22):2227-36.
26/01/2008
RFA sostituisce chirurgia nell’HCC precoce?
Sustained complete response and complications rates after radiofrequency ablation of very early hepatocellular carcinoma in cirrhosis: Is resection still the treatment of choice? Livraghi T, Meloni F, Di Stasi M, Rolle E, Solbiati L, Tinelli C, Rossi S. Hepatology. 2007 Nov 15; [Epub ahead of print]
23/01/2008
Utile la profilassi per HBV in pazienti che si sottopongono a chemio per linfoma
Hepatitis B prophylaxis in patients undergoing chemotherapy for lymphoma: a decision analysis model.Saab S, Dong MH, Joseph TA, Tong MJ. Hepatology. 2007 Oct;46(4):1049-56.
12/01/2008
Fattori predittivi di riattivazione dell’HBV
Predictive Factors for Reactivation of Hepatitis B Following Hepatitis B e Antigen Seroconversion in Chronic Hepatitis B. Gastroenterology 2007; 133: 1458-65
08/01/2008
Encefalopatia epatica: ruolo dell’ECAD
Randomized controlled study of extracorporeal albumin dialysis for hepatic encephalopathy in advanced cirrhosis. Hassanein TI, Tofteng F, Brown RS Jr, McGuire B, Lynch P, Mehta R, Larsen FS, Gornbein J, Stange J, Blei AT. Hepatology. 2007 Nov 1; [Epub ahead of print]