07/12/2007
Attività del Crohn e gravidanza….
Disease Activity in Pregnant Women With Crohn's Disease and Birth Outcomes: A Regional Danish Cohort Study.Nørgård B, Hundborg HH, Jacobsen BA, Nielsen GL, Fonager K. Am J Gastroenterol. 2007 Jun 15; [Epub ahead of print]
07/12/2007
Attività del Crohn e gravidanza….
Disease Activity in Pregnant Women With Crohn's Disease and Birth Outcomes: A Regional Danish Cohort Study.Nørgård B, Hundborg HH, Jacobsen BA, Nielsen GL, Fonager K. Am J Gastroenterol. 2007 Jun 15; [Epub ahead of print]
22/09/2007
Certolizumab nel trattamento del Crohn: i risultati del PRECISE study
Certolizumab pegol for the treatment of Crohn's disease.Sandborn WJ, Feagan BG, Stoinov S, Honiball PJ, Rutgeerts P, Mason D, Bloomfield R, Schreiber S; PRECISE 1 Study Investigators. N Engl J Med. 2007 Jul 19;357(3):228-38.
22/09/2007
Certolizumab nel trattamento del Crohn: i risultati del PRECISE study
Certolizumab pegol for the treatment of Crohn's disease.Sandborn WJ, Feagan BG, Stoinov S, Honiball PJ, Rutgeerts P, Mason D, Bloomfield R, Schreiber S; PRECISE 1 Study Investigators. N Engl J Med. 2007 Jul 19;357(3):228-38.
16/09/2007
Meta-analisi sulla mortalità nel Crohn
Meta-analysis: mortality in Crohn's disease.Canavan C, Abrams KR, Mayberry JF. Aliment Pharmacol Ther. 2007 Apr 15;25(8):861-70.
16/09/2007
Meta-analisi sulla mortalità nel Crohn
Meta-analysis: mortality in Crohn's disease.Canavan C, Abrams KR, Mayberry JF. Aliment Pharmacol Ther. 2007 Apr 15;25(8):861-70.
22/08/2007
Adalimumab efficace nel Crohn non responder all’infliximab
Adalimumab maintenance therapy for Crohn's disease with intolerance or lost response to infliximab: an open-label study.Peyrin-Biroulet L, Laclotte C, Bigard MA. Aliment Pharmacol Ther. 2007 Mar 15;25(6):675-80.
03/08/2007
IBD non associate ad aumentato rischio cardiovascolare
Inflammatory bowel disease is not associated with increased intimal media thickening. Maharshak N, Arbel Y, Bornstein NM, Gal-Oz A, Gur AY, Shapira I, Rogowski O, Berliner S, Halpern Z, Dotan I.Am J Gastroenterol. 2007 May;102(5):1050-5.
01/08/2007
Meta-analisi sulla terapia medica nell’UC lieve -moderata
Meta-analysis: the efficacy of rectal beclomethasone dipropionate vs. 5-aminosalicylic acid in mild to moderate distal ulcerative colitis. Manguso F, Balzano A.Aliment Pharmacol Ther. 2007 Jul 1;26(1):21-9.
27/07/2007
Trovato il recettore per l’AIEC nell’ileo di malati di Crohn
CEACAM6 acts as a receptor for adherent-invasive E. coli, supporting ileal mucosa colonization in Crohn disease. Barnich N, Carvalho FA, Glasser AL, Darcha C, Jantscheff P, Allez M, Peeters H, Bommelaer G, Desreumaux P, Colombel JF, Darfeuille-Michaud A.J Clin Invest. 2007 May 24; [Epub ahead of print]
25/07/2007
Review sistematica : omega 3 e mantenimento del Crohn ....
Omega 3 fatty acids (fish oil) for maintenance of remission in Crohn's disease. Turner D, Zlotkin Sh, Shah P, Griffiths A.Cochrane Database Syst Rev. 2007 Apr 18;(2):CD006320.
22/07/2007
Accuratezza diagnostica della calprotectina fecale....
Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy. von Roon AC, Karamountzos L, Purkayastha S, Reese GE, Darzi AW, Teare JP, Paraskeva P, Tekkis PP.Am J Gastroenterol. 2007 Apr;102(4):803-13.
19/07/2007
IBD: talidomide efficace e sicura....
Efficacy and safety of thalidomide in children and young adults with intractable inflammatory bowel disease: long-term results.Lazzerini M, Martelossi S, Marchetti F, Scabar A, Bradaschia F, Ronfani L, Ventura A. Aliment Pharmacol Ther. 2007 Feb 15;25(4):419-27.
26/06/2007
Adalimumab induce la remissione nei non responder all’infliximab
Adalimumab Induction Therapy for Crohn Disease Previously Treated with Infliximab. A Randomized Trial. Sandborn WJ, Rutgeerts P, Enns R, Hanauer SB, Colombel JF, Panaccione R, D'Haens G, Li J, Rosenfeld MR, Kent JD, Pollack PF. Ann Intern Med. 2007 Apr 30; [Epub ahead of print]
18/06/2007
La displasia nella UC è identificabile durante l’esame endoscopico…
Are dysplasia and colorectal cancer endoscopically visible in patients with ulcerative colitis? Rubin DT, Rothe JA, Hetzel JT, Cohen RD, Hanauer SB. Gastrointest Endosc. 2007 Apr 20; [Epub ahead of print]
11/06/2007
Identificata la mutazione responsabile del M.di Crohn
Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Rioux JD, Xavier RJ, Taylor KD, Silverberg MS, Goyette P, Huett A, Green T, Kuballa P, Barmada MM, Datta LW, Shugart YY, Griffiths AM, Targan SR, Ippoliti AF, Bernard EJ, Mei L, Nicolae DL, Regueiro M, Schumm LP, Steinhart AH, Rotter JI, Duerr RH, Cho JH, Daly MJ, Brant SR. Nat Genet. 2007 Apr 15; [Epub ahead of print]
10/06/2007
Colite ulcerosa: l’infliximab non previene la colectomia
Infliximab for the treatment of ulcerative colitis: outcomes in Oxford from 2000 to 2006S. L. JAKOBOVITS, D. P. JEWELL, S. P. L. TRAVIS. Alimentary Pharmacology & Therapeutics 2007; 25 (9): 1055–1060.
09/06/2007
La dilatazione endoscopica è utile nel trattamento delle stenosi da MC
Endoscopic balloon dilatation of intestinal strictures in Crohn's disease: Safe alternative to surgery. Ajlouni Y, Iser JH, Gibson PR.J Gastroenterol Hepatol. 2007 Apr;22(4):486-90.
03/06/2007
La mortalità dei pz con CU non differisce dalla popolazione generale
Overalland cause-specific mortality in ulcerative colitis: meta-analysis ofpopulation-based inception cohort studies. Jess T, Gamborg M, Munkholm P,Sorensen TI.AmJ Gastroenterol. 2007 Mar;102(3):609-17.
30/05/2007
SCOPERTA PROTEINA CHE PREVIENE FLOGOSI INTESTINO
Epithelial NEMOlinks innate immunity to chronic intestinal inflammation. Nenci A, Becker C,Wullaert A, Gareus R, van Loo G, Danese S, Huth M, Nikolaev A, Neufert C,Madison B, Gumucio D, Neurath MF, Pasparakis M.CHAR(13) + CHAR(10)Nature. 2007 Mar 29;446(7135):557-61. Epub 2007 Mar14.
16/05/2007
Review sistematica sul natalizumab nel trattamento della m. di Crohn
12/05/2007
Colite Ulcerosa: un nuovo trattamento....
23/04/2007
White cell scan predice gravità della colite ulcerosa
Determiningthe proximal extent of ulcerative colitis: white cell scan correlates well withhistological assessmentV.SUBRAMANIAN,A. BANERJEE, N. BEHARRY, M. J. G. FARTHING, G. POLLOK.AlimentaryPharmacology & Therapeutics 2007 25 (4), 441-446.
22/03/2007
Review sistematica su terapia con infliximab nella colite ulcerosa
Systematic review:Infliximab therapy in ulcerative colitis. Gisbert JP, Gonzalez-Lama Y, Mate J. Aliment Pharmacol Ther. 2007 Jan1;25(1):19-37.
16/03/2007
Update sull’epidemiologia delle IBD nella contea di Olmsted
CHAR(13) + CHAR(10)Updateon the incidence and prevalence of Crohn's disease and ulcerative colitis inOlmsted County, Minnesota, 1940-2000. Loftus CG, Loftus EV Jr, Harmsen WS, Zinsmeister AR,Tremaine WJ, Melton LJ 3rd, Sandborn WJ. Inflamm Bowel Dis. 2006 Dec 19; [Epubahead of print]
13/03/2007
RCU severa: terapia con steroidi in infusione o in bolo? Un RCT...
ContinuousInfusion Versus Bolus Administration of Steroids in Severe Attacks ofUlcerative Colitis: A Randomized, Double-Blind Trial. Bossa F, Fiorella S, Caruso N,Accadia L, Napolitano G, Valvano MR, Andriulli A, Annese V. Am J Gastroenterol.2006 Dec 11; [Epub ahead of print]
08/03/2007
Colite ulcerosa: La riattivazione del CMV è frequente ma si autolimita
Cytomegalovirus Is FrequentlyReactivated and Disappears Without Antiviral Agents in Ulcerative ColitisPatients. Matsuoka K, Iwao Y, Mori T, Sakuraba A, Yajima T, Hisamatsu T,Okamoto S, Morohoshi Y, Izumiya M, Ichikawa H, Sato T, Inoue N, Ogata H, HibiT.AmJ Gastroenterol. 2006 Dec 11; [Epub ahead of print]
28/02/2007
Saccharomyces boulardii è utile nel trattamento delle IBD
Saccharomycesboulardii inhibits inflammatory bowel disease by trapping T cells in mesentericlymph nodes. Dalmasso G, Cottrez F, Imbert V, Lagadec P, Peyron JF, Rampal P,Czerucka D, Groux H. Gastroenterology. 2006 Dec;131(6):1812-25.
24/02/2007
Appendicectomia e rischio di sviluppare Crohn….
The risk of developing Crohn's disease after an appendectomy: a population-based cohort study in Sweden and Denmark.Kaplan GG, Pedersen BV, Andersson RE, Sands BE, Korzenik J, Frisch M. Gut. 2007 Oct;56(10):1387-92.
14/02/2007
Gli immunosoppressori riducono l’immunogenicità dell’infliximab ?
Risks and benefits of combining immunosuppressives and biological agents in inflammatory bowel disease: is the synergy worth the risk? Hanauer SB. Gut. 2007 Sep;56(9):1181-3.
11/02/2007
La sovraesposizione ai raggi X aumenta il rischio di cancro nelle IBD?
Quantifying exposure to diagnostic medical radiation in patients with inflammatory bowel disease: are we contributing to malignancy? E. Newnham, E. Hawkes, A. Surender, S. L. James, R. Gearry & P. R. Gibson Alimentary Pharmacology & Therapeutics 26 (7), 1019–1024.
10/02/2007
Probiotici ed IBD...un nuovo meccanismo di azione!
Probioticsin inflammatory bowel disease: yet another mechanism of action?Fiocchi C. Gastroenterology. 2006 Dec;131(6):2009-12.
10/02/2007
Meta-analisi sulla risposta al placebo nella CU
Meta-Analysis of the Placebo Response in Ulcerative Colitis.Garud S, Brown A, Cheifetz A, Levitan EB, Kelly CP. Dig Dis Sci. 2007 Oct 13; [Epub ahead of print]
08/02/2007
IBD e gravidanza ...una meta-analisi
AMeta-analysis on the Influence of Inflammatory Bowel Disease on Pregnancy. CornishJA, Tan EK, Teare J, Teoh TG, Rai R, Clark SK, Tekkis PP. Gut. 2006 Dec 21;[Epub ahead of print]
07/02/2007
Differenze nella gestione del Crohn tra esperti e medici di base
Differences in the management of Crohn's disease among experts and community providers, based on a national survey of sample case vignettes. Esrailian E, Spiegel BM, Targownik LE, Dubinsky MC, Targan SR, Gralnek IM. Aliment Pharmacol Ther. 2007 Oct 1;26(7):1005-18.
06/02/2007
Review sistematica su IBD e rischio cardiovascolare
InflammatoryBowel Disease Is Not a Risk Factor for Cardiovascular Disease Mortality:Results from a Systematic Review and Meta-Analysis. Dorn SD,Sandler RS. Am J Gastroenterol. 2006 Dec 11; [Epub ahead of print]
06/02/2007
L’infezione da C.difficile peggiora l’outcome delle IBD
Excess hospitalization burden associated with Clostridium difficile in patients with Inflammatory Bowel Disease. Ananthakrishnan AN, McGinley EL, Binion DG. Gut. 2007 Sep 28; [Epub ahead of print]
03/02/2007
Consensus Europeo su diagnosi e trattamento della malattia di Crohn
(Praga, 24 settembre 2004)
30/01/2007
FRUTTA, VERDURA E PESCE RIDUCONO IL RISCHIO DI MORBO DI CROHN
Imbalances in dietary consumption of fatty acids, vegetables, and fruits are associated with risk for Crohn's disease in children. Amre DK, D'Souza S, Morgan K, Seidman G, Lambrette P, Grimard G, Israel D, Mack D, Ghadirian P, Deslandres C, Chotard V, Budai B, Law L, Levy E, Seidman EG. Am J Gastroenterol. 2007 Sep;102(9):2016-25.
29/01/2007
Trattamento della Colite Ulcerosa distale e della proctite
LINEE-GUIDA PER IL TRATTAMENTO DELLA COLITE ULCEROSADISTALE E DELLA PROCTITE ULCEROSACHAR(13) + CHAR(10)CHAR(13) + CHAR(10)Clinicalguidelines for the medical management of left-sided ulcerative colitis andulcerative proctitis: summary statement.Regueiro M,Loftus EV Jr, Steinhart AH, Cohen RD. Inflamm Bowel Dis. 2006Oct;12(10):972-8.CHAR(13) + CHAR(10)CHAR(13) + CHAR(10)CHAR(13) + CHAR(10)CHAR(13) + CHAR(10)CHAR(13) + CHAR(10)
20/01/2007
Anomalie degli enzimi epatici nei pazienti con IBD
Abnormal HepaticBiochemistries in Patients With Inflammatory Bowel Disease Flavia D. Mendes, Cynthia Levy, Felicity B.Enders, Edward V. Loftus Jr., Paul Angulo, and Keith D. Lindor. Am JGastroenterol 2006;101:1-7
08/01/2007
Una storia familiare di IBD non influenza il fenotipo della malattia
Are There Any Differences in Phenotype or Disease Course Between Familial and Sporadic Cases of Inflammatory Bowel Disease? Results of a Population-Based Follow-Up Study.Henriksen M, Jahnsen J, Lygren I, Vatn MH, Moum B; the IBSEN Study Group. Am J Gastroenterol. 2007 Aug 21;102(9):1955-1963.
08/01/2007
Una storia familiare di IBD non influenza il fenotipo della malattia
Are There Any Differences in Phenotype or Disease Course Between Familial and Sporadic Cases of Inflammatory Bowel Disease? Results of a Population-Based Follow-Up Study.Henriksen M, Jahnsen J, Lygren I, Vatn MH, Moum B; the IBSEN Study Group. Am J Gastroenterol. 2007 Aug 21;102(9):1955-1963.
05/01/2007
Review sistematica su steroidodipendenza nella CU
Review article: the management of steroid dependency in ulcerative colitis. Porro GB, Cassinotti A, Ferrara E, Maconi G, Ardizzone S. Aliment Pharmacol Ther. 2007 Sep 15;26(6):779-94.
05/01/2007
Review sistematica su steroidodipendenza nella CU
Review article: the management of steroid dependency in ulcerative colitis. Porro GB, Cassinotti A, Ferrara E, Maconi G, Ardizzone S. Aliment Pharmacol Ther. 2007 Sep 15;26(6):779-94.
02/01/2007
EnteroTC: correlazione con il quadro endoscopico e la PCR nel M.di Crohn
Quantitativemeasurement and visual assessment of ileal Crohn's disease activity by computedtomography enterography: correlation with endoscopic severity and C reactiveprotein.Colombel JF, SolemCA, Sandborn WJ, Booya F, Loftus EV Jr, Harmsen WS, Zinsmeister AR, Bodily KD,Fletcher JG.Gut. 2006Nov;55(11):1561-7. Epub 2006 Apr 28.